Current Members

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JianZhong Liu

JianZhong Liu

JianZhong Liu

Date of Birth: Oct 13, 1988

Mobile Phone: +86-13501182807

Email: [email protected]

For details, see:

http://sklnbd.bjmu.edu.cn/team/jiaoning/eng/index.php/category/view?id=203

Education

2015.9-2018: Ph. D. Student, Candidate

Organic and Medicinal Chemistry, Peking University.

Advisor: Prof. Ning Jiao.

2012.9-2015.6: Master. D.

Medicinal Chemistry, Chengdu Institute of Biology, University of Chinese Academy of Sciences.

Advisor: Prof. Xiaoxia Lu. Including: 2013.9-2015.3, South China University of Technology. (Co-training student, Director: Prof. Wei Zeng).

2007.9-2011.6: Bachelor. D.

Pharmacy, Henan University.

Advisor: Prof. Fuli Zhang.

Publications

  1. Jianzhong Liu, Xiao Luo, Xu Qiu, Cheng Zhang, Jun Pan, Ning Jiao*. Selective C(Ar)-C(Alkenyl) single Bond Amination of Styrenes: Highly Efficient Approach to Primary Anilines and phenols. (to be submited).
  2. Jianzhong Liu, Cheng Zhang, Ziyao Zhang, Xiaojin Wen, Xiaodong Dou, Jialiang Wei, Xu Qiu, Song, Song, Ning Jiao*. Nitromethane as a nitrogen donor in Schmidt-type formation of amides and nitriles. Science, 2019, 10.1126/science.aay950.
  3. Jianzhong Liu, Xu Qiu, Xiaoqiang Huang, Xiao Luo, Cheng Zhang, Jialiang Wei, Jun Pan, Yujie Liang, Yuchao Zhu, Qixue Qin, Song Song, Ning Jiao*. From alkylarenes to anilines via site-directed carbon–carbon amination. Nature Chemistry. 2019, 11, 71.
  4. Jianzhong Liu+, Xiaojin Wen+, Chong Qin+, Xinyao Li, Xiao Luo, Ao Sun, Bencong Zhu, Song Song*, Ning Jiao*. Oxygenation of Simple Olefins through Selective Allylic C-C Bond Cleavage: A Direct Approach to Cinnamyl Aldehydes. Angew. Chem. Int. Ed. 2017, 56, 11940.
  5. Jianzhong Liu, Kai Wu, Tao Shen, Yujie Liang, Miancheng Zou, Yuchao Zhu, Xinwei Li, Xinyao Li, Ning Jiao*. Fe-Catalyzed Amination of (Hetero)Arenes with a Redox-Active Aminating Reagent under Mild Conditions. Chem.–Eur. J. 2017, 23, 563.
  6. Jianzhong Liu, Ying Xie, Wei Zeng*, Dongen Lin*, Yuanfu Deng*, Xiaoxia Lu*. Pd(II)-Catalyzed Pyridine N-Oxides Directed Arylation of Unactivated Csp3−H Bonds. J. Org. Chem.2015, 80, 4618.
  7. Yeerlan Adeli, Kaimeng Huang, Yujie Liang, Yangye Jiang,Jianzhong Liu, Song Song, Cheng-Chu Zeng*, Ning Jiao*. Electrochemically Oxidative C-C Bond Cleavage of Alkylarenes for Anilines Synthesis. ACS Catal. 2019, 9, 2063.
  8. Jun Pan+, Xinyao Li+, Fengguirong Lin,Jianzhong Liu, Ning Jiao*. Chemoselective Nitrosylation of Anilines and Alkynes via Fragmentary or Complete NO Incorporation. Chem. 2018, 4, 1427.
  9. Tao Shen, Bencong Zhu, Fengguirong Lin, Jun Pan, Jialiang Wei, Xiao Luo,Jianzhong Liu, Ning Jiao*. Direct Synthesis of Structurally Divergent Indole Alkaloids from Simple Chemicals. Chin. J. Chem. 2018, 36, 815.
  10. Xiaoyang Wang, Xu Qiu, Jialiang Wei,Jianzhong Liu, Song Song, Wen Wang*, Ning Jiao*.Cu-Catalyzed Aerobic Oxidative Sulfuration/Annulation Approach to Thiazoles via Multiple Csp3-H Bond Cleavage. Org. Lett. 2018, 20, 2632.
  11. Song Song, Yiqun Zhang, Adeli, Yeerlan, Bencong Zhu,Jianzhong Liu, Ning Jiao* Cs2CO3-Catalyzed Aerobic Oxidative Cross-Dehydrogenative Coupling of Thiols with Phosphonates and Arenes. Angew. Chem. Int. Ed. 2017, 56, 2487.
  12. Miancheng Zou,Jianzhong Liu, Conghui Tang, Ning Jiao*. Rh-Catalyzed N-O Bond Cleavage of Anthranil: A C-H Amination Reagent for Simultaneous Incorporation of Amine and a Functional Group. Org. Lett. 2016, 18, 3030.
  13. Conghui Tang, Miancheng Zou,Jianzhong Liu, Xiaojin Wen, Xiang Sun, Yiqun Zhang, Ning Jiao*. Rh-Catalyzed Direct Amination of Unactivated C(sp3)-H bond with Anthranils Under Mild Conditions. Chem. Eur. J. 2016, 22, 11165.
  14. Yu-Feng Liang, Xiaoyang Wang, Conghui Tang, Tao Shen,Jianzhong Liu, Ning Jiao*. NHPI and palladium co-catalyzed aerobic oxidative acylation of arenes through a radical process. Chem. Commun. 2014, 52, 1416.

 

Patents:

  1. Ning Jiao,Jianzhong Liu, Song Song. An efficient synthetic method for anilines and its derivatives. Chinese Patent, application number: 201811064304.9, application date 12.09.2018.
  2. Ning Jiao, Jianzhong Liu, Cheng Zhang. The application of highly efficient nitrogenantion reagent. Chinese Patent, application number: 201910943969.5, application date 09.30.2019.

Honor & Awards

  1. Merit Student of University of Chinese Academy of Sciences, 2013.
  2. Peking University Innovation Award, 2016.
  3. Peking University Excellent Research Award, 2016.
  4. National Scholarship (for PhD student, top 2%), 2018.
  5. Excellent Graduate student of Peking University, 2018 .
  6. Post Award of the 13th International Symposium on Activation of Dioxygen and Homogeneous Catalysis, 2018.

Research Interest

Organometallic Chemistry, C-H/C-C bond functionalization; Radical Chemistry.

Discovery & development of new reagent and new strategy for nitrogen-atom (NH/NH2 group) installation.

Pharmaceutical diversification (the synthesis and late-stage modification of bioactive natural products and drugs).

Academic Activities

  1. The 8thNational Organic Chemistry Conference, poster presentation, Chongqing, China. Dec. 2013.
  2. The 10thNational Organic Chemistry Conference, poster presentation, Shenzhen, China. Dec. 2017
  3. The 13thInternational Symposium on Activation of Dioxygen and Homogeneous Catalysis, poster presentation, Xi’an, China. June. 2018.